Prof. Dr.-Ing. Wolf-Georg Klöckner Chemie- und Umwelttechnik

Summer terms

• Chemical Process Engineering
• Chemistry for Energy-, Environmental and Process Engineering
• Environmental Chemistry and Analytics

Winter terms

• Orientation and Methods
• Water and air purification
• Chemistry & Chemistry for Bioprocess Engineering 

• Hydromechanical characterization of aerobic bioreactors by determination of maximum local energy dissipation rates
• Utilization of fermentation residue and biomass by Hydrothermal Carbonization (HTC): Watts in Grass!? - Interreg
• Optimization of sparger design and stirrer geoemtry for high oxygen transfer rates in large-scale bioreactors
• Recycling and Circular Economy as part of the Competence Center Industry 4.0

University of Applied Sciences Osnabrück, Professor of Chemical and Environmental Engineering since April 2026

Covestro Deutschland AG, Senior Project Manager for Circular Economy (2020 – 2026)

• Upscaling of recycling processes for polyurethanes. Evaluation of chemical routes, process development and transfer to piloting scale

• Responsible for overall process development for production of bio-based aniline 

   

Bayer AG, Engineering & Technology, Expert in Fermentation and Cell Cultivation (2013 – 2020)

• Development of new bio-based production processes
• Development of an automated screening system for mammalian cells
• Responsible for design, -optimization and upscaling of large scale microbial fermentation processes
• Supervision of post-docs, lab-workers and trainees

• Ph.D. in Biochemical Engineering (Dr.-Ing), RWTH Aachen University, Department of Biochemical Engineering
• Diploma thesis at Bayer Technology Services
• Degree in Process Engineering, RWTH Aachen University
• Borchers Medal, RWTH Aachen University

• A. Schulte, A. Jordan, W. Klöckner, M. Schumacher, B. Corves, J. Büchs: Effect of High-Speed Shaking on Oxygen Transfer in Shake Flasks. Biotechnol Journal, 2025, 20(4), 1860-6768 

• R. Gamboa-Suasnavart, N. Valdez-Cruz, G. Gaytan-Ortega, G. Cereceda, & D. Cabrera-Santos, & L. López-Griego, W. Klöckner, J. Büchs, M. Trujillo-Roldán: The metabolic switch can be activated in a recombinant strain of Streptomyces lividans by a low oxygen transfer rate in shake flasks. Microbial Cell Factories, 2018, 17(1), 189

• K. Meier, W. Klöckner, B. Bonhage, E. Antonov, L. Regestein, J. Büchs: Correlation for the maximum oxygen transfer capacity in shake flasks for a wide range of operating conditions and for different culture media, Biochemical Engineering Journal, 2016, 228-235

• N. Raven, S. Rasche, C. Kuehn, T. Anderlei, W. Klöckner, F. Schuster, M. Henquet, D. Bosch, J. Büchs, R. Fischer, S. Schillberg: Scaled-up manufacturing of recombinant antibodies produced by plant cells in a 200-L orbitally-shaken disposable bioreactor. Biotechnology & Bioengineering, 2015, 112(2), 308-321

• H. Giese, W. Klöckner, C. Peña, E. Galindo, S. Lotter, K. Wetzel, L. Meissner, C. P. Peter, J. Büchs: Effective shear rates in shake flasks, Chemical Engineering Science, 2014, 102-113

• W. Klöckner, C. Lattermann, F. Pursche, Sören Werner, Dieter Eibl, J. Büchs: Time efficient way to calculate oxygen transfer areas and power input in cylindrical disposable shaken bioreactors. Biotechnology Process, 2014, 30: 1441-1456

• W. Klöckner, R. Gacem, T. Anderlei, N. Raven, S. Schillberg, C. Lattermann, J. Büchs: Correlation between mass transfer coefficient k_La and relevant operating parameters in cylindrical disposable shaken bioreactors on a bench-to-pilot scale. Journal of Biological Engineering, 2013, 7, 28 

• W. Klöckner, S. Diederichs, J. Büchs: Orbitally shaken single-use bioreactors. In: R. Eibl and T. Eibl (Eds.): Disposable Bioreactors II, Springer, 2013

• W. Klöckner, J. Büchs: Advances in shaking technologies. Trends in Biotechnology, 2012, 30(6), 307-314

• W. Klöckner, S. Tissot, F. Wurm, J. Büchs: Power input correlation to characterize the hydrodynamics of cylindrical orbitally shaken bioreactors. Biochemical Engineering Journal, 2012, 65, 63-69

• N. Mehmood, E. Olmos, J.-L. Goergen, F. Blanchard, P. Marchal, W. Klöckner, J. Büchs, S. Delaunay: Decoupling of oxygen transfer and power dissipation for the study of the production of pristinamycins by Streptomyces pristinaespiralis in shaking flasks. Biochemical Engineering Journal, 2012, 68, 25-33

• C. Núnez, C. Pena, W. Klöckner, A. Hernández-Eligio, A. V. Bogachev, S. Moreno, J. Guzmán, J. Büchs, G. Espin: Alginate synthesis in Azotobacter vinelandii is increased by reducing the intracellular production of ubiquinone. Applied Microbiology and Biotechnology, 2012

• W. Klöckner, J. Büchs: Shake-Flask Bioreactors. In: Murray Moo-Young (Eds.): Comprehensive Biotechnology, Elsevier, (2.17), 2011, 213-226

• N. Mehmood, E. Olmos, J.-L. Goergen, F. Blanchard, D. Ullisch, W. Klöckner, J. Büchs, S. Delaunay: Oxygen supply controls the onset of pristinamycins production by Streptomyces pristinaespiralis in shaking flasks. Biotechnology and Bioengineering, 2011, 108(9), 2151-2161

• F.F. Krull, M. Hechinger, W. Klöckner, M. Verhuelsdonk, F. Buchbender, H. Giese, T. Melin: Ionic liquid imbibition of ceramic nanofiltration membranes, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2009, 182-190