Downstreamprocessing

Faculty

Faculty of Engineering and Computer Science

Version

Version 1 of 23.02.2026.

Module identifier

11B2142

Module level

Bachelor

Language of instruction

German

ECTS credit points and grading

5.0

Module frequency

only summer term

Duration

1 semester

 

 

Brief description

Within the module, knowledge and skills in the field of product purification (downstream processes) are deepened. This includes methods for the extraction and purification of biosynthetic products after the application of biotechnological processes such as fermentation or bioconversion, cell separation, isolation and enrichment.

Teaching and learning outcomes

- Transfer and application of knowledge from the modules "Bioprocess Engineering" and "Product Purification" to complex processes for the manufacture of biotechnological products
- Mass and energy balances
- Design of apparatus
- Modelling processes with Excel
- In-depth study of processes and apparatus in purification technology, e.g: - Evaporation - Crystallisation - Extraction - Adsorption and absorption
- chromatography

Practical course:
- Isolation of chlorophyll a by means of extraction and chromatography
- Extraction of proteins using aqueous 2-phase systems
- Crystallisation

Overall workload

The total workload for the module is 150 hours (see also "ECTS credit points and grading").

Teaching and learning methods
Lecturer based learning
Workload hoursType of teachingMedia implementationConcretization
45LecturePresence-
15Laboratory activityPresence-
Lecturer independent learning
Workload hoursType of teachingMedia implementationConcretization
30Work in small groups-
20Study of literature-
20Preparation/follow-up for course work-
20seminar paper-
Graded examination
  • oral exam or
  • Project Report, written or
  • Written examination
Ungraded exam
  • Field work / Experimental work
Exam duration and scope

Graded examination performance:

  • Written examination: see the applicable study regulations
  • Oral examination: see the general section of the examination regulations
  • Project report, written: 5 reports, each approx. 6 pages, accompanying explanation: approx. 20 minutes

Ungraded examination performance:

  • Experimental work: Experiment: approx. 3 experiments

Literature

Sattler, K.; Thermische Trennverfahren, VCH-Wiley, Weinheim, 2001 Schwister, K., Leven, V.; Verfahrenstechnik für Ingenieure, Carl Hanser Verlag, München , 2013

Goedecke, R. (Hrsg.); Fluidverfahrenstechnik, Wiley-VCH, Weinheim, 2011 Chmiel, H.; Bioprozesstechnik , Spektrum Akademischer Verlag, Heidelberg, 2011

Storhas; Bioverfahrensentwicklung, Wiley-VCH, Weinheim, 2012

Applicability in study programs

  • Bioengineering in the Food Industry
    • Bioengineering in the Food Industry B.Sc. (01.09.2025)

    Person responsible for the module
    • Schmitz, Ulrich
    Teachers
    • Schmitz, Ulrich